Hepatitis E virus: an underdiagnosed cause of chronic hepatitis in renal transplant recipients.
نویسندگان
چکیده
Hepatitis E virus (HEV) infection can evolve to chronic hepatitis in immunocompromised patients leading to rapidly progressive cirrhosis. Proper diagnosis is therefore important, as reducing immunosuppressive therapy can allow clearance of the virus. We report a case of chronic HEV infection in a renal transplant recipient that went undiagnosed for many years, discuss the therapeutic options, and review the current available literature.
منابع مشابه
Genome Sequence of a Hepatitis E Virus of Genotype 3e from a Chronically Infected Kidney Transplant Recipient
Hepatitis E virus (HEV) is an emerging cause of acute and chronic hepatitis in immunocompromised patients in Europe. We report the genome sequence of a genotype 3e HEV from a chronically infected kidney transplant recipient in southeastern France, the second HEV genome sequence from a transplant recipient and the first of subtype 3e.
متن کاملبررسی تأثیر عفونت هپاتیت ویروسی B و C بر بقای کلیه پیوندی در بیماران دریافتکننده کلیه
Background and Aim: Chronic liver disease and its complications are major problems in renal transplant recipients. Hepatitis B and C virus infections are currently the main causes of chronic liver disease in this group, and these may affect allograft outcome. Whether hepatitis B and C virus infections after renal transplantation adversely affect graft and patient survival, remains controver...
متن کاملSeroclearance of hepatitis B surface antigen following hepatitis E exacerbation on chronic hepatitis E and B dual infection in a renal transplant recipient: a case report
BACKGROUND Hepatitis E virus infection usually causes an acute and self-resolving hepatitis. In areas where chronic hepatitis B virus infection is prevalent, acute hepatitis E virus superinfection on chronic hepatitis B virus infection occurs sporadically. In recent years, however, chronic hepatitis E virus infection has been recognized in patients under immunosuppressant therapy. To the best o...
متن کاملChronic hepatitis E with cirrhosis in a kidney-transplant recipient.
To the Editor: Hepatitis E virus (HEV) is an important cause of acute viral hepatitis worldwide.1 Kamar et al. in this issue of the Journal2 and others3,4 have recently suggested that HEV infection might result in chronic hepatitis in immunocompromised patients. We report a rapidly progressing case of cirrhosis in a renal-transplant recipient with chronic HEV infection. A 52-year-old man who ha...
متن کاملSeroprevalence of Hepatitis E among Iranian Renal Transplant Recipients
BACKGROUND Renal transplant recipients are known to be susceptible to viral infections, with more severe clinical presentations compared to healthy persons. Hepatitis E is generally a self-limited disease, which is caused by hepatitis E virus. Recently, hepatitis E has become more important in organ transplant recipients, because of new findings regarding the potential for chronic infections in...
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عنوان ژورنال:
- Transplant infectious disease : an official journal of the Transplantation Society
دوره 14 1 شماره
صفحات -
تاریخ انتشار 2012